Due to the heterogeneity of Electronic Health Record (EHR) standards, decision-making teams, who are not experts in health information, express confusion in selecting and applying these resources in their data platforms. Therefore, a group of experts has analyzed the strengths and weaknesses regarding the design, modeling capabilities, flexibility, and implemented resources of three relevant standards based on Detailed Clinical Models: OpenEHR, ISO 13606, and HL7 FHIR. Thus, it was concluded that: (1) they are useful for the purposes for which they have been designed and present deficiencies in those for which they have not been designed; (2) they are functionally compatible in platforms and health data methodologies developed from an independent perspective of the standards; and (3) they are conceptually and technically compatible with each other, so the choice of one or the other does not have a high impact as long as it starts from the one richer in modeling capabilities and flexibility.